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BDBM336300 US9744172, Compound UNC00000516A

SMILES: CNc1ncc2c(nn(CC3CC[C@@H](CC3)N(C)C)c2n1)-c1ccccc1

InChI Key: InChIKey=UQFJOGJOWAFMER-SKHKEOPYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336300   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336300
PNG
(US9744172, Compound UNC00000516A)
Show SMILES CNc1ncc2c(nn(CC3CC[C@@H](CC3)N(C)C)c2n1)-c1ccccc1
Show InChI InChI=1S/C21H28N6/c1-22-21-23-13-18-19(16-7-5-4-6-8-16)25-27(20(18)24-21)14-15-9-11-17(12-10-15)26(2)3/h4-8,13,15,17H,9-12,14H2,1-3H3,(H,22,23,24)/t15?,17-
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair