BindingDB logo
myBDB logout

BDBM336303 US9744172, Compound UNC00000547A

SMILES: CNc1ncc2c(nn(CCCCCN)c2n1)-c1ccccc1

InChI Key: InChIKey=CMHWBYDGCDMHJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336303
PNG
(US9744172, Compound UNC00000547A)
Show SMILES CNc1ncc2c(nn(CCCCCN)c2n1)-c1ccccc1
Show InChI InChI=1S/C17H22N6/c1-19-17-20-12-14-15(13-8-4-2-5-9-13)22-23(16(14)21-17)11-7-3-6-10-18/h2,4-5,8-9,12H,3,6-7,10-11,18H2,1H3,(H,19,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair