BindingDB logo
myBDB logout

BDBM336304 US9744172, Compound UNC00000585A

SMILES: CNc1ncc2c(nn(CCCCN)c2n1)-c1ccccc1

InChI Key: InChIKey=QBIGADAYYPDODC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336304   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336304
PNG
(US9744172, Compound UNC00000585A)
Show SMILES CNc1ncc2c(nn(CCCCN)c2n1)-c1ccccc1
Show InChI InChI=1S/C16H20N6/c1-18-16-19-11-13-14(12-7-3-2-4-8-12)21-22(15(13)20-16)10-6-5-9-17/h2-4,7-8,11H,5-6,9-10,17H2,1H3,(H,18,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair