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BDBM336316 US9744172, Compound UNC00000345A

SMILES: NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCN4CCOCC4)nc23)CC1

InChI Key: InChIKey=RFKMRWREQLLFCY-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336316
PNG
(US9744172, Compound UNC00000345A)
Show SMILES NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCN4CCOCC4)nc23)CC1
Show InChI InChI=1S/C24H33N7O/c25-20-8-6-18(7-9-20)17-31-23-21(22(29-31)19-4-2-1-3-5-19)16-27-24(28-23)26-10-11-30-12-14-32-15-13-30/h1-5,16,18,20H,6-15,17,25H2,(H,26,27,28)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+4n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair