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BDBM336318 US9744172, Compound UNC00000261A

SMILES: CNc1ncc2c(nn(CC3CC[C@H](O)CC3)c2n1)-c1ccccc1

InChI Key: InChIKey=BJFADWIVXIPKGC-ULCMKKNGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336318   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336318
PNG
(US9744172, Compound UNC00000261A)
Show SMILES CNc1ncc2c(nn(CC3CC[C@H](O)CC3)c2n1)-c1ccccc1
Show InChI InChI=1S/C19H23N5O/c1-20-19-21-11-16-17(14-5-3-2-4-6-14)23-24(18(16)22-19)12-13-7-9-15(25)10-8-13/h2-6,11,13,15,25H,7-10,12H2,1H3,(H,20,21,22)/t13?,15-
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair