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BDBM336323 US9744172, Compound UNC00000475A

SMILES: CCCCCCNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccccc1

InChI Key: InChIKey=BVEQODOWLDSZOY-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336323   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336323
PNG
(US9744172, Compound UNC00000475A)
Show SMILES CCCCCCNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccccc1
Show InChI InChI=1S/C24H34N6/c1-2-3-4-8-15-26-24-27-16-21-22(19-9-6-5-7-10-19)29-30(23(21)28-24)17-18-11-13-20(25)14-12-18/h5-7,9-10,16,18,20H,2-4,8,11-15,17,25H2,1H3,(H,26,27,28)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair