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BDBM336354 US9744172, Compound UNC705A

SMILES: CCCNc1ncc2c(nn(C3CCCCC3)c2n1)-c1ccc(cc1)C(O)=O

InChI Key: InChIKey=YFYJYQSPVSYQJH-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336354   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336354
PNG
(US9744172, Compound UNC705A)
Show SMILES CCCNc1ncc2c(nn(C3CCCCC3)c2n1)-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H25N5O2/c1-2-12-22-21-23-13-17-18(14-8-10-15(11-9-14)20(27)28)25-26(19(17)24-21)16-6-4-3-5-7-16/h8-11,13,16H,2-7,12H2,1H3,(H,27,28)(H,22,23,24)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair