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BDBM336392 US9744172, Compound UNC904A

SMILES: CCCCNc1ncc2c(nn(C3CCCCC3)c2n1)-c1ccc(cc1)S(=O)(=O)NC

InChI Key: InChIKey=FRQJTIWJZKUNAP-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336392   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336392
PNG
(US9744172, Compound UNC904A)
Show SMILES CCCCNc1ncc2c(nn(C3CCCCC3)c2n1)-c1ccc(cc1)S(=O)(=O)NC
Show InChI InChI=1S/C22H30N6O2S/c1-3-4-14-24-22-25-15-19-20(16-10-12-18(13-11-16)31(29,30)23-2)27-28(21(19)26-22)17-8-6-5-7-9-17/h10-13,15,17,23H,3-9,14H2,1-2H3,(H,24,25,26)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair