BindingDB logo
myBDB logout

BDBM336425 US9744172, Compound UNC1172A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key: InChIKey=DRUSBHBLZORBMC-UPDYAAQLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336425   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336425
PNG
(US9744172, Compound UNC1172A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)C(=O)N1CCOCC1
Show InChI InChI=1S/C26H34N6O3/c1-2-3-12-27-26-28-17-22-23(30-32(24(22)29-26)20-8-10-21(33)11-9-20)18-4-6-19(7-5-18)25(34)31-13-15-35-16-14-31/h4-7,17,20-21,33H,2-3,8-16H2,1H3,(H,27,28,29)/t20?,21-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair