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BDBM336429 US9744172, Compound UNC1183A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)C(=O)N1CCCC1

InChI Key: InChIKey=BJXOXUIDCDDIGS-UPDYAAQLSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336429   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336429
PNG
(US9744172, Compound UNC1183A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)C(=O)N1CCCC1
Show InChI InChI=1S/C26H34N6O2/c1-2-3-14-27-26-28-17-22-23(30-32(24(22)29-26)20-10-12-21(33)13-11-20)18-6-8-19(9-7-18)25(34)31-15-4-5-16-31/h6-9,17,20-21,33H,2-5,10-16H2,1H3,(H,27,28,29)/t20?,21-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair