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BDBM336453 US9744172, Compound UNC1223A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(NC(=O)NC2CCCC2)cc1

InChI Key: InChIKey=FLLVOSJZTHYYIZ-RAKDUWMASA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336453   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336453
PNG
(US9744172, Compound UNC1223A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(NC(=O)NC2CCCC2)cc1
Show InChI InChI=1S/C27H37N7O2/c1-2-3-16-28-26-29-17-23-24(33-34(25(23)32-26)21-12-14-22(35)15-13-21)18-8-10-20(11-9-18)31-27(36)30-19-6-4-5-7-19/h8-11,17,19,21-22,35H,2-7,12-16H2,1H3,(H,28,29,32)(H2,30,31,36)/t21?,22-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair