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BDBM336456 US9744172, Compound UNC1144A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=HMZAXKJRAZRAQM-JMOIINNLSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336456
PNG
(US9744172, Compound UNC1144A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C31H45N7O3S/c1-2-3-17-32-31-33-22-28-29(35-38(30(28)34-31)25-9-11-26(39)12-10-25)23-7-13-27(14-8-23)42(40,41)37-20-15-24(16-21-37)36-18-5-4-6-19-36/h7-8,13-14,22,24-26,39H,2-6,9-12,15-21H2,1H3,(H,32,33,34)/t25?,26-
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair