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BDBM336474 US9744172, Compound UNC1236A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)NCCC(O)=O

InChI Key: InChIKey=NKHJIRLUSGFGRL-WEBLMRDCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336474   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336474
PNG
(US9744172, Compound UNC1236A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)NCCC(O)=O
Show InChI InChI=1S/C24H32N6O5S/c1-2-3-13-25-24-26-15-20-22(29-30(23(20)28-24)17-6-8-18(31)9-7-17)16-4-10-19(11-5-16)36(34,35)27-14-12-21(32)33/h4-5,10-11,15,17-18,27,31H,2-3,6-9,12-14H2,1H3,(H,32,33)(H,25,26,28)/t17?,18-
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair