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BDBM336475 US9744172, Compound UNC1281A

SMILES: CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)NCCC(=O)N1CCOCC1

InChI Key: InChIKey=OXMSXVGTMVDROT-RAKDUWMASA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336475
PNG
(US9744172, Compound UNC1281A)
Show SMILES CCCCNc1ncc2c(nn(C3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)NCCC(=O)N1CCOCC1
Show InChI InChI=1S/C28H39N7O5S/c1-2-3-13-29-28-30-19-24-26(33-35(27(24)32-28)21-6-8-22(36)9-7-21)20-4-10-23(11-5-20)41(38,39)31-14-12-25(37)34-15-17-40-18-16-34/h4-5,10-11,19,21-22,31,36H,2-3,6-9,12-18H2,1H3,(H,29,30,32)/t21?,22-
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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair