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BDBM336495 US9744172, Compound UNC1323A

SMILES: CCCCCNC(=O)c1ccc(cc1)N(C)S(=O)(=O)c1ccc(cc1)-c1nn(C2CC[C@H](O)CC2)c2nc(NCCCC)ncc12

InChI Key: InChIKey=MKQPYBKNENLKFR-OITQPWSSSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336495   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336495
PNG
(US9744172, Compound UNC1323A)
Show SMILES CCCCCNC(=O)c1ccc(cc1)N(C)S(=O)(=O)c1ccc(cc1)-c1nn(C2CC[C@H](O)CC2)c2nc(NCCCC)ncc12
Show InChI InChI=1S/C34H45N7O4S/c1-4-6-8-22-35-33(43)25-9-13-26(14-10-25)40(3)46(44,45)29-19-11-24(12-20-29)31-30-23-37-34(36-21-7-5-2)38-32(30)41(39-31)27-15-17-28(42)18-16-27/h9-14,19-20,23,27-28,42H,4-8,15-18,21-22H2,1-3H3,(H,35,43)(H,36,37,38)/t27?,28-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair