BDBM336569 N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-::US9744173, Example 75

SMILES C[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)c1nc(NC(=O)c2cn(C)cn2)cs1

InChI Key InChIKey=NPGXSCFUAULWBJ-PUTJDCORSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336569   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM336569(N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6- | US...)
Affinity DataIC50:  1.82E+4nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent