BDBM336662 US9745283, Example 91

SMILES CCn1c(=O)c(cn(-c2ccc(F)cc2)c1=O)C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1

InChI Key InChIKey=BINSYFWLLMFVFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336662   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ignyta

US Patent
LigandPNGBDBM336662(US9745283, Example 91)
Affinity DataIC50:  55nMAssay Description:The cMET kinase assay was performed in 384-well Fluotrac 200 HiBase microplates using the HTRF KinEASE assay described above for AXL except that the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Ignyta

US Patent
LigandPNGBDBM336662(US9745283, Example 91)
Affinity DataIC50: <10nMAssay Description:The ability of compounds to inhibit the kinase activity of recombinant human baculovirus-expressed AXL was measured by homogeneous TRF (HTRF) using C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent