BDBM336771 2-{[(2R,5R)-5-{[4-(2,2- difluoroethoxy)pyridin-2- yl]oxy}-2-methylpiperidin-1- yl]carbonyl}-3-(2H-1,2,3- triazol-2-yl)pyridine::US9745284, 33

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ncccc1-n1nccn1)Oc1cc(OCC(F)F)ccn1

InChI Key InChIKey=OGZGPRBWSZBKCM-GDBMZVCRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336771   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336771(2-{[(2R,5R)-5-{[4-(2,2- difluoroethoxy)pyridin-2- ...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336771(2-{[(2R,5R)-5-{[4-(2,2- difluoroethoxy)pyridin-2- ...)
Affinity DataIC50:  71nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent