BDBM336778 4-(2-methylpropoxy)-2-{[(3R,6R)-6- methyl-1-{[2-(2H-1,2,3-triazol-2- yl)phenyl]carbonyl}piperidin-3- yl]oxy}pyridine::US9745284, 42

SMILES CC(C)COc1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1

InChI Key InChIKey=SPJKAZUUQZUCHC-UYAOXDASSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336778   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336778(4-(2-methylpropoxy)-2-{[(3R,6R)-6- methyl-1-{[2-(2...)
Affinity DataIC50:  5.61E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336778(4-(2-methylpropoxy)-2-{[(3R,6R)-6- methyl-1-{[2-(2...)
Affinity DataIC50:  134nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent