BDBM336792 1-(2-{[(2R,5R)- 5-{[4- (difluoromethoxy) pyridin-2-yl]oxy}-2- methylpiperidin-1- yl]carbonyl}phenyl) cyclopropane- carbonitrile::US9745284, 56

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1C1(CC1)C#N)Oc1cc(OC(F)F)ccn1

InChI Key InChIKey=XGCOWCPOPSXVDV-NVXWUHKLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336792   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336792(1-(2-{[(2R,5R)- 5-{[4- (difluoromethoxy) pyridin-2...)
Affinity DataIC50:  1.15E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336792(1-(2-{[(2R,5R)- 5-{[4- (difluoromethoxy) pyridin-2...)
Affinity DataIC50:  11nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent