BDBM337024 US9745291, Compound 70::US9765068, Compound 70
SMILES OC(CNC(=O)COc1ccc2cnn(C3CCNCC3)c2c1)CN1CCc2ccccc2C1
InChI Key InChIKey=BPCBLCQMCNDJJR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 337024
Affinity DataIC50: <100nMAssay Description:Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair