BDBM337144 US9745291, Compound 190::US9765068, Compound 190
SMILES CN1CCN(CC1)c1cccc(OCC(=O)NC[C@@H](O)CN2CCc3ccccc3C2)c1
InChI Key InChIKey=WVPXMECBKCWVTO-HSZRJFAPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 337144
Affinity DataIC50: <100nMAssay Description:Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme
US Patent
Epizyme
US Patent
Affinity DataIC50: <100nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair