BDBM337247 (2S)-2-hydroxy-N-[3-(4-methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyridazin-6-yl]propanamide::US9745304, Example 16

SMILES COc1nccc2oc(cc12)-c1cnc2ccc(NC(=O)[C@H](C)O)nn12

InChI Key InChIKey=PJWUSWRCXKIDCP-VIFPVBQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337247   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337247((2S)-2-hydroxy-N-[3-(4-methoxyfuro[3,2-c]pyridin-2...)
Affinity DataIC50:  10nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337247((2S)-2-hydroxy-N-[3-(4-methoxyfuro[3,2-c]pyridin-2...)
Affinity DataIC50:  10nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent