BDBM337256 N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6-yl]- 2-[2- (trifluoromethyl)phenyl]acetamide::US9745304, Example 25

SMILES FC(F)(F)c1ccccc1CC(=O)Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1

InChI Key InChIKey=YZTIMMGUZXDJJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337256   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337256(N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  31nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337256(N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  31nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent