BDBM337260 N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6-yl]- 3-(4-fluorophenyl)propanamide::US9745304, Example 29

SMILES Fc1ccc(CCC(=O)Nc2ccc3ncc(-c4cc5ccccc5o4)n3n2)cc1

InChI Key InChIKey=DVKRXTYEDGWONB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 337260   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337260(N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  44nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337260(N-[3-(1-benzofuran-2- yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50:  44nMAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent