BDBM337269 2-[2-(3,5-dimethoxyphenyl)ethyl]-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine::US9745311, Example 5

SMILES COc1ccc(cc1)-c1cc2nc(CCc3cc(OC)cc(OC)c3)cnc2[nH]1

InChI Key InChIKey=AFZZOHTZUUATIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337269   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337269(2-[2-(3,5-dimethoxyphenyl)ethyl]-6-(4-methoxypheny...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337269(2-[2-(3,5-dimethoxyphenyl)ethyl]-6-(4-methoxypheny...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337269(2-[2-(3,5-dimethoxyphenyl)ethyl]-6-(4-methoxypheny...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent