BDBM337272 4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazin-6-yl}-N,N-dimethylbenzamide::US9745311, Example 7

SMILES COc1cc(CCc2cnc3[nH]c(cc3n2)-c2ccc(cc2)C(=O)N(C)C)cc(OC)c1

InChI Key InChIKey=ARLLFDSIHLNJAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337272   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337272(4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337272(4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3...)
Affinity DataIC50:  300nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337272(4-{2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent