BDBM337339 7-(2-(3,5-Dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl)pyrido[2,3-b]pyrazine::US9745311, Example 66

SMILES COc1cc(CCc2cnc3[nH]c(cc3n2)-c2cnc3nccnc3c2)cc(OC)c1

InChI Key InChIKey=JNJVOUUWDJTCNM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337339   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337339(7-(2-(3,5-Dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337339(7-(2-(3,5-Dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: >2.00E+3nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM337339(7-(2-(3,5-Dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: <100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent