BindingDB logo
myBDB logout

BDBM337375 6-[4-(2,3-Dihydrofuro[3,2-c]pyridin-4-yloxy)phenyl]-1,5-dimethylpyrimidine-2,4(1H,3H)-dione, trifluoroacetate salt (13)::US9745317, 13

SMILES: CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1c(C)c(C)c(C)c(C)c1P(C(C)(C)C)C(C)(C)C

InChI Key: InChIKey=RCRYEYMHBHPZQD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337375   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337375
PNG
(6-[4-(2,3-Dihydrofuro[3,2-c]pyridin-4-yloxy)phenyl...)
Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)-c1c(C)c(C)c(C)c(C)c1P(C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C33H53P/c1-19(2)26-17-27(20(3)4)30(28(18-26)21(5)6)29-24(9)22(7)23(8)25(10)31(29)34(32(11,12)13)33(14,15)16/h17-21H,1-16H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
46.1n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)

More data for this
Ligand-Target Pair