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BDBM337382 US9745317, 20

SMILES: Cc1cc(Oc2ncnc3CCCc23)ccc1-c1c(C)ncnc1C

InChI Key: InChIKey=ZBFUNBKLXXAHPC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337382
PNG
(US9745317, 20)
Show SMILES Cc1cc(Oc2ncnc3CCCc23)ccc1-c1c(C)ncnc1C
Show InChI InChI=1S/C20H20N4O/c1-12-9-15(25-20-17-5-4-6-18(17)23-11-24-20)7-8-16(12)19-13(2)21-10-22-14(19)3/h7-11H,4-6H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
446n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)

More data for this
Ligand-Target Pair