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BDBM337388 US9745317, 26

SMILES: Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3OCCc23)cc1C#N

InChI Key: InChIKey=OVPWTXZFXSLPPC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337388   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337388
PNG
(US9745317, 26)
Show SMILES Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3OCCc23)cc1C#N
Show InChI InChI=1S/C20H16N4O3/c1-11-18(12(2)23-24-19(11)25)15-4-3-14(9-13(15)10-21)27-20-16-6-8-26-17(16)5-7-22-20/h3-5,7,9H,6,8H2,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
162n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


Article DOI: 10.1021/jm049187l
More data for this
Ligand-Target Pair