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BDBM337641 4-Hydroxy-6-(methyl(propyl)amino)pyridazin-3(2H)-one::US9750748, 11

SMILES: CCCN(C)c1cc(O)c(=O)[nH]n1

InChI Key: InChIKey=BFRWTCZZJNYVCQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337641   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-amino-acid oxidase (DAAO)


(Homo sapiens (Human))
BDBM337641
PNG
(4-Hydroxy-6-(methyl(propyl)amino)pyridazin-3(2H)-o...)
Show SMILES CCCN(C)c1cc(O)c(=O)[nH]n1
Show InChI InChI=1S/C8H13N3O2/c1-3-4-11(2)7-5-6(12)8(13)10-9-7/h5H,3-4H2,1-2H3,(H,9,12)(H,10,13)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 180n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...


US Patent US9750748 (2017)

More data for this
Ligand-Target Pair