BDBM337697 3-(2,3-Dichlorobenzyl)-2,4-dioxo-1-[4-(1H-pyrazol-3-yl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid::US9751843, 71

SMILES OC(=O)c1cn(-c2ccc(cc2)-c2cc[nH]n2)c(=O)n(Cc2cccc(Cl)c2Cl)c1=O

InChI Key InChIKey=CFXHPUDQAFBTHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337697   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337697(3-(2,3-Dichlorobenzyl)-2,4-dioxo-1-[4-(1H-pyrazol-...)
Affinity DataIC50:  427nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent