BDBM337740 Ethyl 1-{4-[(5S)-5-(acetamidomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}-3-[2-chloro-3-(trifluoromethyl)benzyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (S enantiomer)::US9751843, 111

SMILES CCOC(=O)c1cn(-c2ccc(cc2)N2C[C@H](CNC(C)=O)OC2=O)c(=O)n(Cc2cccc(c2Cl)C(F)(F)F)c1=O

InChI Key InChIKey=XBRKODDCLMASEK-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337740   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337740(Ethyl 1-{4-[(5S)-5-(acetamidomethyl)-2-oxo-1,3-oxa...)
Affinity DataIC50:  540nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent