BDBM337797 Ethyl 2,4-dioxo-1-[4-(2-oxoimidazolidin-1-yl)phenyl]-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate (R enantiomer)::US9751843, 191

SMILES CCOC(=O)c1cn(-c2ccc(cc2)N2CCNC2=O)c(=O)n([C@@H]2CCc3c2cccc3C(F)(F)F)c1=O

InChI Key InChIKey=HBHMGZNADCTAJC-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337797   

TargetChymase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM337797(Ethyl 2,4-dioxo-1-[4-(2-oxoimidazolidin-1-yl)pheny...)
Affinity DataIC50:  120nMAssay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent