BDBM338201 US9751854, Compound I-382::US9802960, Compound I-382

SMILES Cc1nc(Nc2cc(ccn2)-c2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)nc(n1)C1CC1

InChI Key InChIKey=YZQBWQOBFKPFMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338201   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338201(US9751854, Compound I-382 | US9802960, Compound I-...)
Affinity DataIC50: <10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM338201(US9751854, Compound I-382 | US9802960, Compound I-...)
Affinity DataIC50: <10nMAssay Description:100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent