BDBM338344 (3S,6R)-2-[3-Fluoro-4-(4- [1,2,4]triazol-4-yl-piperidin-1-yl)- benzyl]-3-methyl-6-phenyl- [1,2]thiazinane 1,1-dioxide::US9751873, Example 31

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(N2CCC(CC2)n2cnnc2)c(F)c1

InChI Key InChIKey=KCWSJKCYVHUZIW-UQBPGWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 338344   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338344((3S,6R)-2-[3-Fluoro-4-(4- [1,2,4]triazol-4-yl-pipe...)
Affinity DataIC50:  64nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent