BDBM338415 US9751873, Example 103::US9751873, Example 109::methyl (3S,4S)-3-[2,5-difluoro-4- [[(3S,6R)-3-methyl-1,1-dioxo-6- phenyl-thiazinan-2- yl]methyl]phenyl]tetrahydropyran-4- carboxylate

SMILES COC(=O)[C@H]1CCOC[C@@H]1c1cc(F)c(CN2[C@@H](C)CC[C@H](c3ccccc3)S2(=O)=O)cc1F

InChI Key InChIKey=MMGKAZJDUTWPJK-AEUPAERQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338415   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338415(US9751873, Example 103 | US9751873, Example 109 | ...)
Affinity DataIC50:  50nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338415(US9751873, Example 103 | US9751873, Example 109 | ...)
Affinity DataIC50:  54nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent