BDBM338445 2-[2,5-difluoro-4-[[(3S,6R)-3- methyl-1,1-dioxo-6-phenyl- thiazinan-2-yl]methyl]phenyl]-2- (oxetan-3-yl)ethanol::US9751873, Example 132::US9751873, Example 133

SMILES C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(cc1F)C(CO)C1COC1

InChI Key InChIKey=INXAONFPYSTUEC-FZVNPLTNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 338445   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338445(2-[2,5-difluoro-4-[[(3S,6R)-3- methyl-1,1-dioxo-6-...)
Affinity DataIC50:  25nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM338445(2-[2,5-difluoro-4-[[(3S,6R)-3- methyl-1,1-dioxo-6-...)
Affinity DataIC50:  51nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent