BDBM338582 US9751881, Example 111
SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCC2(CC1)CCN(CC2)c1cnc(cn1)C#N
InChI Key InChIKey=RHNJDXLPEVWAPL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 338582
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 9.62nMAssay Description:Assay Protocol: The ROMK channel functional thallium flux assay was performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells were ...More data for this Ligand-Target Pair