BDBM338688 3-(trans-2-((cyclopropyl- methyl)- amino)cyclopropyl)-N-(3- fluorophenyl)benzamide trifluoroacetate::US9751885, 122

SMILES Fc1cccc(NC(=O)c2cccc(c2)C2CC2NCC2CC2)c1

InChI Key InChIKey=JZZWGBIRMOKQJG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 338688   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338688(3-(trans-2-((cyclopropyl- methyl)- amino)cycloprop...)
Affinity DataIC50: <100nMAssay Description:A test compound dissolved in 2.5% DMSO was added by 4 μL to 3 μL reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338688(3-(trans-2-((cyclopropyl- methyl)- amino)cycloprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM338688(3-(trans-2-((cyclopropyl- methyl)- amino)cycloprop...)
Affinity DataIC50: >1.00E+4nMAssay Description:A test compound dissolved in 4% DMSO was added by 12.5 μL to 25 μL reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing 400 ng...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent