BDBM339130 US10201546, Example 65b

SMILES COc1nc2ccc(cc2c(Cl)c1OC1CCN(C)CC1)[C@](O)(c1cnnn1C)c1ccc(C)nc1C

InChI Key InChIKey=HNUNFPAUYBPPQR-HHHXNRCGSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 339130   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339130(US10201546, Example 65b)
Affinity DataIC50: >6.00E+3nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339130(US10201546, Example 65b)
Affinity DataKd:  5.30E+3nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent