BDBM339519 US10202339, Compound 298

SMILES Cc1cc(F)ccc1NS(=O)(=O)c1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=YIDHKYHZYZYVQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339519   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Agios Pharmaceuticals

US Patent
LigandPNGBDBM339519(US10202339, Compound 298)
Affinity DataIC50:  5.50E+3nMAssay Description:Assays were conducted in a volume of 76 μl assay buffer (150 mM NaCl, 10 mM MgCl2, 20 mM Tris pH 7.5, 0.03% bovine serum albumin) as follows in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent