BDBM339565 US10202339, Compound 9
SMILES Fc1ccccc1NC(=O)Nc1cc(ccc1-c1ccsc1)S(=O)(=O)Nc1ccccc1
InChI Key InChIKey=TYOMBKOOGXJHCG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 339565
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Homo sapiens (Human))
Agios Pharmaceuticals
US Patent
Agios Pharmaceuticals
US Patent
Affinity DataIC50: 550nMAssay Description:Compounds were assayed for IDH2 R140Q inhibitory activity through a cofactor depletion assay. Compounds were preincubated with enzyme, then the react...More data for this Ligand-Target Pair