BDBM33958 dihydroxy benzoyl naphthyl hydrazone (DHBNH) analogue, 5
SMILES COc1ccc2ccccc2c1\C=N\NC(=O)c1ccc(cc1)C(C)(C)C
InChI Key InChIKey=YHONUWNAKKJDIE-BUVRLJJBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 33958
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University
Rutgers University
Affinity DataIC50: 2.00E+3nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University
Rutgers University
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair