BDBM339619 US10202339, Compound 63

SMILES Fc1ccccc1-c1ccc(cc1NC(=O)Nc1cccc(c1)C(F)(F)F)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=VBPOOTAEDMOTSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339619   

TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Homo sapiens (Human))
Agios Pharmaceuticals

US Patent
LigandPNGBDBM339619(US10202339, Compound 63)
Affinity DataIC50:  5.50E+3nMAssay Description:Compounds were assayed for IDH2 R140Q inhibitory activity through a cofactor depletion assay. Compounds were preincubated with enzyme, then the react...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent