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BDBM339915 US9758480, 147

SMILES: CS(=O)(=O)NC(=O)c1ccc(NC(=O)[C@@H]2[C@@H](CCN2C(=O)[C@H]2CC[C@@H](CC2)[C@H](N)CF)C2CCCCC2)cc1

InChI Key: InChIKey=AZDABJAPHQIUFJ-GILAWRQCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor XI


(Homo sapiens (Human))
BDBM339915
PNG
(US9758480, 147)
Show SMILES CS(=O)(=O)NC(=O)c1ccc(NC(=O)[C@@H]2[C@@H](CCN2C(=O)[C@H]2CC[C@@H](CC2)[C@H](N)CF)C2CCCCC2)cc1
Show InChI InChI=1S/C28H41FN4O5S/c1-39(37,38)32-26(34)20-11-13-22(14-12-20)31-27(35)25-23(18-5-3-2-4-6-18)15-16-33(25)28(36)21-9-7-19(8-10-21)24(30)17-29/h11-14,18-19,21,23-25H,2-10,15-17,30H2,1H3,(H,31,35)(H,32,34)/t19-,21-,23-,24+,25-/m0/s1
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MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 205n/an/an/an/an/an/a



SUMITOMO DAINIPPON PHARMA CO., LTD.

US Patent


Assay Description
0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145...


US Patent US9758480 (2017)

More data for this
Ligand-Target Pair