BDBM339921 US9758480, 186::tert-Butyl [(1S)-1-(trans-4-{[(2S,3S)-3-cyclohexyl-2-({2-[(morpholin-4-ylsulfonyl)carbamoyl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]carbonyl}cyclohexyl)-2-fluoroethyl]carbamate

SMILES N[C@H](CF)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@H]([C@H]1C(=O)Nc1ccc2[nH]c(C(O)=O)c(Cl)c2c1)c1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339921   

TargetCoagulation factor XI(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM339921(US9758480, 186 | tert-Butyl [(1S)-1-(trans-4-{[(2S...)
Affinity DataIC50:  60nMAssay Description:0.35 μg/mL human FXIa was allowed to react with a substrate and a test compound in a 30 mmol/L HEPES buffer solution (pH 7.4) that contained 145...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent