BDBM339946 5-(6-fluoro-1H-indol-3- yl)pyridin-2-amine::US9758505, 15

SMILES Nc1ccc(cn1)-c1c[nH]c2cc(F)ccc12

InChI Key InChIKey=FYKQPLJCHAANRG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339946   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Iteos Therapeutics

US Patent
LigandPNGBDBM339946(5-(6-fluoro-1H-indol-3- yl)pyridin-2-amine | US975...)
Affinity DataIC50:  1.10E+3nMAssay Description:The compounds of formula I inhibit the enzymatic activity of human TDO2.To measure the TDO2 activity, the procedure described in Dolusic et al. J. Me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent