BDBM339976 (S)-5-((2-Aminopropyl)amino)-3-(5-(2-(2-oxopyrrolidin-1-yl)ethyl)-1H-indol-2-yl)pyrazine-2-carboxamide::US9775839, 6.1

SMILES C[C@H](N)CNc1cnc(C(N)=O)c(n1)-c1cc2cc(CCN3CCCC3=O)ccc2[nH]1

InChI Key InChIKey=VOGLQXVDTHAXNP-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339976   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM339976((S)-5-((2-Aminopropyl)amino)-3-(5-(2-(2-oxopyrroli...)
Affinity DataIC50:  3.70nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent